Compare the 2026 Mercedes-Benz E-Class E 350 vs E 450 - Springfield, MO

2026 E-Class E 350 vs E 450 4MATIC

2026 Mercedes-Benz E-Class E 350

  • Standard Engine2.0L I-4 Turbo w/ Mild Hybrid
  • Horsepower255 hp
  • MPG (city/hwy) *25 / 33
  • Seats5
  • DrivetrainRear-Wheel Drive
  • Wheels Size18-inch 5-spoke

2026 Mercedes-Benz E-Class E 450 4MATIC

  • Standard Engine3.0L I-6 Turbo w/ Mild Hybrid
  • Horsepower375 hp
  • MPG (city/hwy) *23 / 33
  • Seats5
  • Drivetrain4MATIC® All-Wheel Drive
  • Wheels Size19-inch AMG 5-spoke

Specs at a Glance

The Mercedes E-Class remains one of today's highest-rated midsize luxury sedans. Few models in the segment can match its performance, innovation, and overall luxuriousness. When shopping for a new E-Class, some drivers will be deciding between the E 350 and the E 450 trim levels. Here's an overview of how these two trims compare.

Performance

Powering the E 350 is a 2.0-liter, turbocharged four-cylinder engine with mild-hybrid assist. It develops 255 horsepower and 295 lb-ft of torque. Impressive fuel efficiency makes the E 350 great for everyday driving. A nine-speed automatic transmission seamlessly feeds power to the wheels. Meanwhile, adaptive suspension dampers promote precise handling and a silky smooth ride. A 4MATIC AWD system is available as an option.

If you hunger for more performance, step up to the more powerful E 450. Underneath its hood rests a 3.0-liter, turbocharged inline-six engine with mild-hybrid assist. Mercedes-Benz tunes the engine to deliver 375 horsepower and 369 lb‑ft of torque. Like the E 350, the E 450 features a nine-speed automatic transmission. However, all-wheel drive becomes standard equipment.

Appearance

Many drivers are drawn to this sedan's upscale appearance. Sporty AMG styling is now standard, accentuating the E 350's muscular profile. A star-pattern grille adds a signature touch to the front fascia. Mercedes also equips the E 350 with a standard panorama roof and 18-inch alloy wheels. Expect the E 450 to have a similar look.

Features

The E 350's plush cabin comes loaded with must-have creature comforts, including dual-zone automatic climate control and heated front seats. You'll also be surrounded by plenty of modern tech features. Mercedes-Benz's intuitive multimedia system features a 14.4‑inch touchscreen with augmented-reality navigation. Other highlights include a suite of advanced safety innovations, a hands-free trunk, a 360-degree camera system, and a wireless charger. The E 450 is similarly equipped.

Visit Us In Springfield, MO

If you have any questions about the 2026 Mercedes E-Class lineup, don't hesitate to contact Elite Automotive Group.

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Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor and installation charges, insurance, and optional equipment, products, packages and accessories. Actual vehicle price may vary by Dealer.

* EPA estimated fuel economy. Compare the estimated mpg to the estimated mpg of other vehicles. You may get different mileage depending on how fast you drive, weather conditions and trip length. Your actual highway mileage will probably be less than the highway estimate.Back to content

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